Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 2.254


Transcription factors associated with TLX1..3_NFIC{dimer}.p2:

Gene SymbolEntrez IDGene Name
TLX1 3195 T-cell leukemia homeobox 1
TLX3 30012 T-cell leukemia homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX3chr5_+_1706688920.185.0e-01Click!
TLX1chr10_+_102881050-0.077.9e-01Click!


Activity profile for motif TLX1..3_NFIC{dimer}.p2.

activity profile for motif TLX1..3_NFIC{dimer}.p2


Sorted Z-values histogram for motif TLX1..3_NFIC{dimer}.p2

Sorted Z-values for motif TLX1..3_NFIC{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX1..3_NFIC{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_27153892 3.090 NM_024014
HOXA6
homeobox A6
chr15_+_76889873 2.531 MORF4L1
mortality factor 4 like 1
chrX_-_128616594 2.507 NM_017413
APLN
apelin
chrX_-_53327473 2.308 NM_015075
IQSEC2
IQ motif and Sec7 domain 2
chr5_+_38481392 2.203 NM_182801
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr22_-_37970902 2.199 NM_002608
PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr19_+_10258642 2.029 NM_001039132
NM_001544
NM_022377
ICAM4


intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)


chr1_-_151630168 1.846 NM_002964
S100A8
S100 calcium binding protein A8
chr3_+_46717826 1.825 NM_147196
TMIE
transmembrane inner ear
chr21_+_45699830 1.821 NM_030582
NM_130444
COL18A1

collagen, type XVIII, alpha 1

chr14_+_72773957 1.790 NM_173462
NDRG2
PAPLN
NDRG family member 2
papilin, proteoglycan-like sulfated glycoprotein
chrX_-_129347101 1.719 NM_178471
GPR119
G protein-coupled receptor 119
chr1_+_219026661 1.713 NM_022746
MOSC1
MOCO sulphurase C-terminal domain containing 1
chr17_-_928960 1.653 ABR
active BCR-related gene
chr19_+_10404110 1.650 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr22_+_40093245 1.625 NM_001145398
TEF
thyrotrophic embryonic factor
chr9_+_135389698 1.546 NM_014694
ADAMTSL2
ADAMTS-like 2
chr15_-_66511488 1.523 NM_001004439
ITGA11
integrin, alpha 11
chr6_+_167658563 1.520 NM_031949
TTLL2
tubulin tyrosine ligase-like family, member 2
chr17_+_75507750 1.511



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
5.93 6.77e-03 GO:0032312 regulation of ARF GTPase activity
4.47 2.05e-02 GO:0032012 regulation of ARF protein signal transduction

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.59 1.09e-03 GO:0044421 extracellular region part
1.46 1.25e-02 GO:0031226 intrinsic to plasma membrane
1.46 1.48e-02 GO:0005887 integral to plasma membrane
1.44 6.11e-05 GO:0044459 plasma membrane part
1.33 3.24e-02 GO:0005576 extracellular region
1.22 1.87e-02 GO:0005886 plasma membrane
1.22 2.33e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
5.93 1.60e-03 GO:0008060 ARF GTPase activator activity